Wordpress Themes

Erythema Multiforme

Erythema Multiforme Alternative names Stevens-Johnson syndrome and also Toxic epidermal necrolysis. Erythema multiforme is a skin problem causng from an allergic reaction. Raised skin that usually appears like targets and are distributed in equal over the body. EM can introduce within a wide spectrum of severity. EM minor illustrates a localized eruption of the skin with mild or no mucosal participation, corresponding to the starting description of von Hebra. EM major and Stevens-Johnson syndrome (SJS) are more harsh mucosal and skin diseases and are eventually life-threatening disorders.

Erythema multiforme is a short-lasting skin disorder which happens as a reaction to an infection or medication. Erythema multiforme mostly attacks young adults but may occur in children or older people. Erythema multiforme chiefly affects to palms, soles, and back of the hands. Sometimes it can expand in to trunk, face, and mouth or in few cases it may visible only in mouth. In some patient spots may occurs in both skin and lips. It also known as Stevens-Johnson syndrome. It relates with fever, muscle aches, and not feeling well. Erythemam multiforme may occurs in any age but mainly children faces it. It effect a characteristic outbreak and usually lesions in the mouth and in another place. It is sometimes called erythema multiforme minor to differentiate it from a related but more severe situation.

Erythema multiforme should be distinguished from urticaria , from which target-shaped blister can arise. However personal urticarial plaques never form lesions, and resolve in 24 hours. Prodromal symptoms are soft or absent in EM minor and can now as a mild nonspecific upper respiratory infection. The hurried onset of a rash normally occurs within 3 days, starting on the extremities balanced with centripetal spreading. Few of the skin patches resembles like a target, i.e. three rings of red, white and pink. Usually the centre of the patch forms a fluid-filled lesion that crusts over within some days.Often, the rash is companies by sores and blisters on the lips. Erythema multiforme follows in irritable round skin blisters mainly on the forearms, hands and less usual, knees and feet. Few or hundreds of blisters appear over 2 to 3 days. Few lesions inclinates scratched or injured skin.

Causes of Erythema Multiforme

Common causes of Erythema Multiforme

  • Allergic reactions(viral, bacterial)
  • Fungal infections
  • Sensitivity to food or drugs.
  • Immunizations.
  • Mycoplasma pneumonia.
  • Cold sores.
  • Herpes of the genitals.
  • Postvaccination( Vaccinia).
  • Malignancy.
  • Hormonal.
  • Collagen vascular disease.
  • Immunologic disorders.

Symptoms of Erythema Multiforme

Common Symptoms of Erythema Multiforme

  • Itching.
  • Fever.
  • General ill feeling.
  • Joint aches.
  • Blisters.
  • Vision abnormalities
  • Dry eyes.
  • Bloodshot eyes.
  • Eye pain.
  • Mouth sores.

Treatment of Erythema Multiforme

Common Treatment of Erythema Multiforme

  • Aggressive monitoring and replacement of fluids and electrolytes are of paramount importance.
  • Provide supportive respiratory care, including suctioning and postural drainage, as needed.
  • Administer empiric antibiotics if clinical evidence of secondary infection exists. Most authorities advise against routine use of prophylactic antibiotics.
  • Use analgesics as needed to control pain, which may be severe.
  • Avoid systemic corticosteroids in minor cases. In severe cases, their use is controversial because they do not improve prognosis and may increase risk of complications.
  • Intravenous Cytoxan , pooled gamma globulin or oral cyclosporin are dramatically helpful.
  • Electrolytes and nutritional support should be started as soon as possible.
  • Toxic epidermal necrolysis (TEN)should be treated like a major burn, with aggressive fluid management, and careful combinations of fluid losses. Strict antisepsis is very important.

Leave a Reply

You must be logged in to post a comment.